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OCD Research
Studies:
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| This is a 12 week study that is
researching changes in glucose metabolism in the brains of people with OCD and/or
depression treated with Paxil (Paroxetine). This study is an extension of previous work
done by this team. It is directed by Drs. Saxena, Brody and Baxter. To date this research
has been very important in identifying specific regions of the brain that are hyper active
in people who have OCD. Activity in these areas normalize with successful treatment. For the participant, this study involves a PET scan of the brain prior to commencing a 12 week regimen of Paxil, and then a second PET scan at the end of the regimen. It also involves having an MRI scan of the brain. Participants will be closely monitored for side effects and efficacy of the medication by their study doctor. For those participants who obtain relief of their symptoms from the Paxil, the study doctor will be glad to refer people to a physician who can continue prescribing the medication, although not necessarily free of charge. Participants who do not obtain relief from their symptoms while on Paxil, will be invited to continue in the study and take a second medication with the Paxil. It is hoped that the combination of the two medications might reduce the OC symptoms. For more information call (310) 794 7305. The study is also being conducted for people who have major depression. Participants with major depression receive a PET scan of the brain prior to commencing twelve weeks of treatment. They will receive a second PET scan of the brain after twelve weeks. Also, during the twelve weeks of treatment, participants will receive an MRI scan of the brain. In this study, participants have a choice of two treatments for their depression. One treatment involves taking the medication, Paxil (Paroxetine), the other treatment is a weekly one-on-one talk therpay called Inter Personal Therapy (IPT). IPT is an effective cognitive therapy specifically designed for the management of depression. For more information call (310) 794-7305. Return to the OCD Reseach Program page. |
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